DETeCD-ADRD guideline provides a structured, multi-tiered approach for diagnosing and evaluating suspected Alzheimer’s Disease and Related Dementias (ADRD) in primary care, emphasizing patient-centered communication, validated cognitive assessments, and individualized laboratory and imaging tests. It also outlines a stepwise diagnostic disclosure process, ensuring patients and caregivers receive clear information abo...

This multicenter study analyzed the largest cohort of patients with MBL-type CPE bacteremia to evaluate CAZAVI+ATM efficacy. Among 206 patients, CAZAVI+ATM reduced 14-day mortality (OR 0.38, p<0.01) and clinical failure (OR 0.4, p<0.01) compared to OAA. No significant difference was found in 30-day mortality. Findings suggest CAZAVI+ATM as a potential alternative where cefiderocol is unavailable.

A decade-long study found that the allometric fat-mass index (AFI) was linked to a 10% higher risk of pancreatic cancer, with a stronger risk in women <55 (HR: 1.45). The allometric lean-mass index (ALI) raised the risk by 7%, with a significant association in men (HR: 1.13). Diabetes was strongly associated with increased pancreatic cancer risk (HR: 1.68), especially in women during the first 6 years (HR: 2.46).

A recent study from Ernakulam district, Kerala, India, found that nearly half of the adults aged 30 yrs & above had hypertension. Dyslipidemia (aOR:12.804), intake of caffeinated drinks (aOR:11.43), poor sleep quality (aOR:2.14) & higher socioeconomic status (aOR:2.14) were associated with hypertension. The study highlights the need for preventive strategies targeting modifiable risk factors to reduce hypertension.

Plasma fibrinogen levels were strongly associated with the severity of diabetic foot ulcers (DFUs), with levels peaking at 720.77 mg/dL for Wagner Grade 5. Elevated fibrinogen levels also correlated with vascular impairment, ulcer depth, C-reactive protein & comorbidities like hypertension &chronic kidney disease. Fibrinogen could serve as a valuable marker for predicting DFU progression & treatment strategies.

Narrow-band UVB (NB-UVB) phototherapy was found to be an effective & well-tolerated treatment for pediatric skin conditions, especially psoriasis and vitiligo, over 10 years. Nearly 91.7% responded positively, with mild & temporary side effects like erythema, itching, and burning in 18.5%. Disease recurrence was absent in 72.2% of patients, reinforcing NB-UVB as a viable option for pediatric dermatological care.