DETeCD-ADRD guideline provides a structured, multi-tiered approach for diagnosing and evaluating suspected Alzheimer’s Disease and Related Dementias (ADRD) in primary care, emphasizing patient-centered communication, validated cognitive assessments, and individualized laboratory and imaging tests. It also outlines a stepwise diagnostic disclosure process, ensuring patients and caregivers receive clear information abo...

This multicenter study analyzed the largest cohort of patients with MBL-type CPE bacteremia to evaluate CAZAVI+ATM efficacy. Among 206 patients, CAZAVI+ATM reduced 14-day mortality (OR 0.38, p<0.01) and clinical failure (OR 0.4, p<0.01) compared to OAA. No significant difference was found in 30-day mortality. Findings suggest CAZAVI+ATM as a potential alternative where cefiderocol is unavailable.

One-third of pediatric atopic dermatitis patients treated with duplimab developed dupilumab-associated ocular surface disease (DAOSD), with tarsal conjunctivitis present in all requiring treatment. Common symptoms included pruritus (75.0%), redness (72.2%), and tearing (58.3%). Elevated serum IgE levels (≥ 3000 kU/L) increased DAOSD risk (OR 4.65). Among those affected, 30% needed anti-inflammatory therapy.

Automated insulin delivery (AID) enhanced glycemic control in insulin-treated type 2 diabetes, reducing glycated hemoglobin levels by 0.9 percentage points over 13 weeks compared to 0.3 points in standard insulin therapy with continuous glucose monitoring. The AID group spent 14% more time in the target glucose range. With low hypoglycemia risk, AID proved to be a viable option for managing type 2 diabetes.

Automated follow-up infarct volume (FIV) analysis was a robust predictor of clinical outcomes in acute ischemic stroke patients undergoing thrombectomy. FIV closely correlated with 90-day functional recovery (modified Rankin Scale) and 24-hour stroke severity (NIH Stroke Scale). Ischemic injury, hemorrhagic transformation, and edema also influenced clinical outcomes, reinforcing FIV’s role in stroke prognosis.

Nicotine product use raised the risk of complications, particularly infections, following cervical disc arthroplasty (CDA). A nationwide analysis found that users had a 37% increased risk of overall complications and a 74% greater infection risk, especially males (aOR = 2.12) and those without diabetes, obesity, and chronic pulmonary disease. These findings underscore the need to assess nicotine use preoperatively.